page_title

Deanne Tibbitts, PhD

Deanne Tibbitts, PhD

Lab Manager
Email

Deanne Tibbitts earned her PhD in Molecular and Medical Genetics from Oregon Health & Science University in 2011. Working at the intersection of genetics and cancer biology, Deanne used both cell culture and animal models to study the molecular basis of leukemia and to test compounds for targeted, anti-leukemic activity. At NCNM, Deanne is the lab manager for NCNM's Helfgott Research Institute and an adjunct faculty member in the Master of Science in Integrative Medicine Research program. She provides instruction in cell culture and serves as a mentor for students who are studying the anti-cancer properties of herbal and natural medicines.


Publications:

Tibbitts DC, Escamilla-Powers JR, Zhang X, Sears RC. 2012. Studying c-Myc serine 62 phosphorylation in leukemia cells: concern over antibody cross-reactivity. Blood 119(22):5334-5.

Arnold HK, Zhang X, Daniel CJ, Tibbitts D, Escamilla-Powers J, Farrell A, Tokarz S, Morgan C, Sears RC. 2009. The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc. EMBO Journal 28(5):500-12.

O'neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, Hardwick J, Welcker M, Meijerink JP, Pieters R, Draetta G, Sears R, Clurman BE, Look AT. 2007. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to {gamma}-secretase inhibitors. Journal of Experimental Medicine 204(8):1813-24.

Malempati S, Tibbitts D, Cunningham M, Akkari Y, Olson S, Fan G, Sears RC. 2006. Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias. Leukemia 20(9):1572-81.

Tibbitts D, Rao RR, Shin S, West FD, Stice SL. 2006. Uniform adherent neural progenitor populations from rhesus embryonic stem cells. Stem Cells and Development 15(2):200-8.